Heart: Changes in mitochondrial DNA control how nuclear DNA mutations are expressed in cardiomyopathy

Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation. When combined with a mutation in nuclear DNA in animals, one mitochondrial DNA variant greatly worsened heart disease, while a different variant had a protective effect.

from Latest Science News -- ScienceDaily https://ift.tt/2N3sytK